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Immunology Antibodies

Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.

Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).

ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.

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Product NameCatalog #App.ReactivityDescription
OAS1 Antibody27-235E, WBHOAS1 (2',5'-oligoadenylate synthetase 1, 40/46kDa)
OAS1 AntibodyXW-7420WBHOligoadenylate synthetase 1 isoform E16
OASL Antibody25-618E, WBHOASL (2'-5'-oligoadenylate synthetase-like)
OMI Antibody3319E, WB, IHC, IFH(CT) IAP inhibitor
OPRK1 Antibody27-232E, WBHOPRK1 (opioid receptor, kappa 1)
OPTN Antibody49-349WB, IHCM, R, POptineurin
ORAI Detection SetPSI-1819WBsee datasheetORAI1, ORAI2, ORAI3, STIM1, STIM2
ORAI-1 Antibody39-871E, WB, IHCH, M(CT) ORAI-1
ORAI1 Antibody4041E, WB, IHC, IFH, M(NT) a T cell calcium channel
ORAI1 Antibody4281E, WB, IHCH, M(CT) a T cell calcium channel
ORAI1 Antibody46-765E, WBHORAI1 / CRACM1
ORAI1 Monoclonal AntibodyPM-5205E, WB, IHC, IFH, M, Ra T cell calcium channel
ORAI1 Monoclonal AntibodyPM-5207E, WB, IHC, IFH, M, Ra T cell calcium channel
ORAI2 Antibody4111E, WB, ICC, IFH, M(CT) a T cell calcium channel
ORAI3 Antibody4117E, WB, ICCH, M, R(NT) a T cell calcium channel
ORAI3 Antibody4215E, WB, ICC, IFH, M(CT) a T cell calcium channel
ORAI3 Monoclonal AntibodyPM-4911E, WB, IHC, IFH, RTransmembrane protein 142C
ORAI3 Monoclonal AntibodyPM-4913E, WBH, RTransmembrane protein 142C
ORM1 AntibodyXW-7661E, WBHa-1-acid glycoprotein 1, AGP 1, Orosomucoid-1, OMD
ORM1 Antibody49-461E, WB, IHC, IF, IPH(CT) Alpha-1-acid Glycoprotein 2
OVA Monoclonal Antibody32-200E, WBn/a
OXSM Antibody26-119E, WBH, M, ROXSM (3-oxoacyl-ACP synthase, mitochondrial)
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