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Immunology Antibodies

Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.

Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).

ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.

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Product NameCatalog #App.ReactivityDescription
Lactoperoxidase Antibody46-861E, WBHLactoperoxidase
LAIR1 Antibody42-518E, WBH(IN) LAIR1
Lano Antibody3001E, WB, IHC, IFH(CT) a member of the LAP family
LAT Antibody45-080E, WBH, M, R(CT) LAT
LAT Monoclonal Antibody49-251WB, IHC, IPHLinker For Activation Of T Cells
LAX Antibody46-862E, WBHLAX
LBP Antibody29-596E, WBHLBP (lipopolysaccharide binding protein)
LCK Monoclonal Antibody49-299WB, IHCHProto-Oncogene Protein Tyrosine Kinase LCK
Lck Monoclonal Antibody32-186E, WBHlymphocyte-specific protein tyrosine kinase
LCN1 Antibody31-310E, WBHLCN1 (lipocalin 1 (tear prealbumin))
LEF1 Antibody45-083E, WBH, M, R(IN) LEF1
LGALS3BP Antibody26-926E, WBH, MLGALS3BP (lectin, galactoside-binding, soluble, 3
LGP2 Antibody46-863E, WBHLGP2
LIME1 Antibody45-085E, WBM(CT) LIME1 (mouse)
LIME1 Monoclonal Antibody49-117WB, IHCHLck Interacting Transmembrane Adaptor 1
LMNB2 Antibody30-194E, WBHLMNB2 (lamin B2)
LMNB2 Antibody26-129E, WBH, M, RLMNB2 (lamin B2)
LNPEP Antibody7055E, WB, IFH(CT) insulin-responsive aminopeptidase
LSP1 Antibody42-530E, WBH, M, R(CT) LSP1
LSP1 Antibody51-012WB, IHCn/aLymphocyte-specific Protein 1
LSP1 Antibody27-211E, WBHLSP1 (lymphocyte-specific protein 1)
LSP1 Antibody42-529E, WBH(IN) LSP1 (aa 261-275)
LTA4H Antibody26-857E, WBH, M, RLTA4H (leukotriene A4 hydrolase)
LTA4H Antibody48-750WB, IHCHLeukotriene A4 Hydrolase
LY6E Antibody42-628E, WBM(IN) LY6E (mouse)
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