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Immunology Antibodies

Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.

Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).

ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.

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Product NameCatalog #App.ReactivityDescription
KCNMA1 Antibody42-044ESee Data(CT) KCNMA1
KHDRBS1 Antibody29-386E, WBHKHDRBS1 (KH domain containing, RNA binding, signal
KIF13B Antibody25-169E, WBH, M, RKIF13B (kinesin family member 13B)
KLF4 Antibody48-521E, WB, IHCHZinc Finger Transcription Factor Hezf
KLF6 Antibody25-271E, WBH, M, RKLF6 (Kruppel-like factor 6)
KLKB1 Antibody30-094E, WBHKLKB1 (kallikrein B, plasma (Fletcher factor) 1)
KLRA1 Antibody4999E, WB, ICC, IFH, M, R(IN) Killer cell lectin-like receptor subfamily A
KLRA1 Antibody4989E, WB, IHC, IFH, M, R(CT) Killer cell lectin-like receptor subfamily A
KLRA1 Antibody26-160E, WBHKLRA1 (killer cell lectin-like receptor subfamily
KLRA2 Antibody5017E, WB, IHC, IFM, R(CT) Killer cell lectin-like receptor subfamily A
KLRA3 Antibody4993E, WBM, R(CT) Killer cell lectin-like receptor subfamily A
KLRG1 Antibody42-156ESee Data(NT) KLRG1
KLRK1 Antibody45-079E, WBH(IN) NKG2D / KLRK1
KRAS Antibody27-016E, WBH, M, R, DsKRAS (v-Ki-ras2 Kirsten rat sarcoma viral oncogene
KRT1 Antibody25-756E, WBHKRT1 (keratin 1 (epidermolytic hyperkeratosis))
KYNU Antibody30-141E, WBHKYNU (kynureninase (L-kynurenine hydrolase))
KYNU Antibody30-140E, WBHKYNU (kynureninase (L-kynurenine hydrolase))
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