Immunology Antibodies
Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.
Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).
ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.
| Product Name | Catalog # | App. | Reactivity | Description |
|---|---|---|---|---|
| ICAM1 Monoclonal Antibody | 51-076 | IHC, IP, FACS | n/a | Intercellular Adhesion Molecule 1 |
| ICOS Antibody | 49-679 | E, IHC | H | Inducible T-cell Co-stimulator |
| ICOS Antibody | 42-123 | E | H | (IN) ICOS |
| ICOSLG Monoclonal Antibody | 49-249 | IHC, FACS | H | Inducible T-cell Co-stimulator Ligand |
| ICSBP1 Antibody | 45-073 | E, WB | H | (CT) ICSBP1 / IRF8 |
| IFI44L Antibody | 30-170 | E, WB, IHC | H | IFI44L (interferon-induced protein 44-like) |
| IFIT2 Antibody | 25-735 | E, WB | H | IFIT2 (interferon-induced protein with tetratricop |
| IFIT3 Antibody | 30-139 | E, WB, IHC | H | IFIT3 (interferon-induced protein with tetratricop |
| IFIT5 Antibody | 26-945 | E, WB | H | IFIT5 (interferon-induced protein with tetratricop |
| IFN-beta Antibody | 4243 | E, WB, IHC, IF | H, M | (IN) beta-interferon |
| IFN-gamma Antibody | XP-5156 | E, WB, N | M | Anti-Murine IFN-γ |
| IFN-gamma Antibody | XP-5157 | E, WB, N | R | Anti-Rat IFN-γ |
| IFN-gamma Antibody | XP-5739-M | E | H | Anti-IFN-γ, monoclonal |
| IFN-gamma Antibody | XP-5155Bt | E, WB | H | Biotin - Anti-Human IFN-γ |
| IFN-gamma Antibody | XP-5156Bt | E, WB | M | Biotin - Anti-Murine IFN-γ |
| IFN-gamma Antibody | XP-5157Bt | E, WB | R | Biotin - Anti-Rat IFN-γ |
| IFN-gamma Antibody | XP-5155 | E, WB, N | H | Anti-Human IFN-γ |
| IFNAR2 Antibody | 46-858 | E | H | IFNAR2 |
| Ig k IgY Antibody | XW-7670 | WB | H | Ig k |
| IgA IgY Antibody | XW-7667 | WB | H | IgA |
| IgG Fc (Human) Antibody | XW-7660 | WB | H | Human IgG Fc |
| IgG Monoclonal Antibody | 32-176 | E, WB | H | |
| IgGm Antibody | XW-7278 | E, WB | H | Immunoglobulin G (IgG), MouseĀ |
| IgGr IgY Antibody | XW-7668 | WB | Rb | IgGr |
| IGHE Antibody | XW-7273 | E | H | Immunoglobulin E (IgE ) |

