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Immunology Antibodies

Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.

Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).

ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.

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Product NameCatalog #App.ReactivityDescription
ICAM1 Monoclonal Antibody51-076IHC, IP, FACSn/aIntercellular Adhesion Molecule 1
ICOS Antibody49-679E, IHCHInducible T-cell Co-stimulator
ICOS Antibody42-123EH(IN) ICOS
ICOSLG Monoclonal Antibody49-249IHC, FACSHInducible T-cell Co-stimulator Ligand
ICSBP1 Antibody45-073E, WBH(CT) ICSBP1 / IRF8
IFI44L Antibody30-170E, WB, IHCHIFI44L (interferon-induced protein 44-like)
IFIT2 Antibody25-735E, WBHIFIT2 (interferon-induced protein with tetratricop
IFIT3 Antibody30-139E, WB, IHCHIFIT3 (interferon-induced protein with tetratricop
IFIT5 Antibody26-945E, WBHIFIT5 (interferon-induced protein with tetratricop
IFN-beta Antibody4243E, WB, IHC, IFH, M(IN) beta-interferon
IFN-gamma AntibodyXP-5156E, WB, NMAnti-Murine IFN-γ
IFN-gamma AntibodyXP-5157E, WB, NRAnti-Rat IFN-γ
IFN-gamma AntibodyXP-5739-MEHAnti-IFN-γ, monoclonal
IFN-gamma AntibodyXP-5155BtE, WBHBiotin - Anti-Human IFN-γ
IFN-gamma AntibodyXP-5156BtE, WBMBiotin - Anti-Murine IFN-γ
IFN-gamma AntibodyXP-5157BtE, WBRBiotin - Anti-Rat IFN-γ
IFN-gamma AntibodyXP-5155E, WB, NHAnti-Human IFN-γ
IFNAR2 Antibody46-858EHIFNAR2
Ig k IgY AntibodyXW-7670WBHIg k
IgA IgY AntibodyXW-7667WBHIgA
IgG Fc (Human) AntibodyXW-7660WBHHuman IgG Fc
IgG Monoclonal Antibody32-176E, WBH
IgGm AntibodyXW-7278E, WBHImmunoglobulin G (IgG), MouseĀ 
IgGr IgY AntibodyXW-7668WBRbIgGr
IGHE AntibodyXW-7273EHImmunoglobulin E (IgE )
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