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Immunology Antibodies

Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.

Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).

ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.

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Product NameCatalog #App.ReactivityDescription
HADH2 Antibody45-068E, WBH(CT) ABAD / HADH2
HAVCR1 Antibody49-280WB, IHCMHepatitis A Virus Cellular Receptor 1
HCK Monoclonal Antibody32-168E, WBHHemopoietic cell kinase
HCK Monoclonal Antibody32-169E, WBHHemopoietic cell kinase
HCLS1 Antibody27-444E, WB, IHCHHCLS1 (hematopoietic cell-specific Lyn substrate 1
HCLS1 Antibody27-647E, WBH, RHCLS1 (hematopoietic cell-specific Lyn substrate 1
HCLS1 Antibody27-445E, WB, IHCHHCLS1 (hematopoietic cell-specific Lyn substrate 1
HDAC9 Antibody29-802E, WB, IHCH, M, DHDAC9 (histone deacetylase 9)
HHEX Antibody27-347E, WB, IHCH, DHHEX (hematopoietically expressed homeobox)
HIST1H1C Antibody30-162E, WBHHIST1H1C (histone cluster 1, H1c)
HIVEP2 Antibody42-246ESee Data(CT) HIVEP2 / MIBP1
HSH2D Antibody42-539E, WBH(IN) HSH2D (aa 325-339)
HSH2D Antibody42-538E, WBH(IN) HSH2D
HSPA4 Antibody26-101E, WBH, M, DHSPA4 (heat shock 70kDa protein 4)
HTR1B Antibody31-114E, WBHHTR1B (5-hydroxytryptamine (serotonin) receptor 1B
HTR1F Antibody31-130E, WBH, RHTR1F (5-hydroxytryptamine (serotonin) receptor 1F
HTR7 Antibody31-118E, WBHHTR7 (5-hydroxytryptamine (serotonin) receptor 7 (
HVCN1 Antibody5875E, WB, IHC, IFH, M, R(CT) Hydrogen voltage-gated channel 1
HVEM (MAb Laury-1) AntibodyXA-1027IP, FCHmonoclonal to HVEM (Laury-1)
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