Immunology Antibodies
Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.
Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).
ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.
| Product Name | Catalog # | App. | Reactivity | Description |
|---|---|---|---|---|
| HADH2 Antibody | 45-068 | E, WB | H | (CT) ABAD / HADH2 |
| HAVCR1 Antibody | 49-280 | WB, IHC | M | Hepatitis A Virus Cellular Receptor 1 |
| HCK Monoclonal Antibody | 32-168 | E, WB | H | Hemopoietic cell kinase |
| HCK Monoclonal Antibody | 32-169 | E, WB | H | Hemopoietic cell kinase |
| HCLS1 Antibody | 27-444 | E, WB, IHC | H | HCLS1 (hematopoietic cell-specific Lyn substrate 1 |
| HCLS1 Antibody | 27-647 | E, WB | H, R | HCLS1 (hematopoietic cell-specific Lyn substrate 1 |
| HCLS1 Antibody | 27-445 | E, WB, IHC | H | HCLS1 (hematopoietic cell-specific Lyn substrate 1 |
| HDAC9 Antibody | 29-802 | E, WB, IHC | H, M, D | HDAC9 (histone deacetylase 9) |
| HHEX Antibody | 27-347 | E, WB, IHC | H, D | HHEX (hematopoietically expressed homeobox) |
| HIST1H1C Antibody | 30-162 | E, WB | H | HIST1H1C (histone cluster 1, H1c) |
| HIVEP2 Antibody | 42-246 | E | See Data | (CT) HIVEP2 / MIBP1 |
| HSH2D Antibody | 42-539 | E, WB | H | (IN) HSH2D (aa 325-339) |
| HSH2D Antibody | 42-538 | E, WB | H | (IN) HSH2D |
| HSPA4 Antibody | 26-101 | E, WB | H, M, D | HSPA4 (heat shock 70kDa protein 4) |
| HTR1B Antibody | 31-114 | E, WB | H | HTR1B (5-hydroxytryptamine (serotonin) receptor 1B |
| HTR1F Antibody | 31-130 | E, WB | H, R | HTR1F (5-hydroxytryptamine (serotonin) receptor 1F |
| HTR7 Antibody | 31-118 | E, WB | H | HTR7 (5-hydroxytryptamine (serotonin) receptor 7 ( |
| HVCN1 Antibody | 5875 | E, WB, IHC, IF | H, M, R | (CT) Hydrogen voltage-gated channel 1 |
| HVEM (MAb Laury-1) Antibody | XA-1027 | IP, FC | H | monoclonal to HVEM (Laury-1) |

