Immunology Antibodies
Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.
Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).
ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.
| Product Name | Catalog # | App. | Reactivity | Description |
|---|---|---|---|---|
| F2 Antibody | 25-721 | E, WB | H, M, R | F2 (coagulation factor II (thrombin)) |
| FADD Antibody | 31-008 | E, WB, IHC | H | FADD (Fas (TNFRSF6)-associated via death domain) |
| FAM82B Antibody | 26-113 | E, WB | H | FAM82B (family with sequence similarity 82, member |
| FAS Antibody | 42-121 | E, WB | H | (IN) FAS / CD95 |
| FAS Monoclonal Antibody | 51-132 | IHC, FACS | n/a | Tumor Necrosis Factor Receptor Superfamily, Member |
| FASLG Antibody | 31-023 | E, WB | H | FASLG (Fas ligand (TNF superfamily, member 6)) |
| FCER1G Antibody | 51-008 | WB, IHC, IP | M, R | High Affinity Immunoglobulin Epsilon Receptor Gamm |
| FCER2 Antibody | 48-480 | E, WB, IHC, IP | H | Fc Fragment Of Ige |
| FCGRT Antibody | 30-199 | E, WB | H | FCGRT (Fc fragment of IgG, receptor, transporter, |
| FEM1A Antibody | 42-022 | E, WB | H | (CT) FEM1A / APRAP |
| FERMT3 Antibody | 42-111 | E, WB | H | (CT) URP2 / kindlin-3 |
| FES Antibody | 26-900 | E, WB | H, M, R | FES (feline sarcoma oncogene) |
| FHOD3 Antibody | 30-191 | E, WB, IHC | H | FHOD3 (formin homology 2 domain containing 3) |
| FKBP8 Antibody | 30-245 | E, WB | H, M, R | FKBP8 (FK506 binding protein 8, 38kDa) |
| FKBP8 Antibody | 30-246 | E, WB | H, M, R | FKBP8 (FK506 binding protein 8, 38kDa) |
| FLJ35848 Antibody | 31-309 | E, WB | H | FLJ35848 (hypothetical protein FLJ35848) |
| FOS Antibody | 31-160 | E, WB | H, M, R, D | FOS (v-fos FBJ murine osteosarcoma viral oncogene |
| FOSL1 Antibody | 27-328 | E, WB, IHC | H, M, R, D | FOSL1 (FOS-like antigen 1) |
| FOXP3 Antibody | 27-688 | E, WB, IHC | H | FOXP3 (forkhead box P3) |
| Foxp3 Monoclonal Antibody | 32-158 | E, WB, FACS | M | Foxp Family Transcription Facto |
| Foxp3 Monoclonal Antibody | 32-157 | WB, FACS | H, M | Foxp Family Transcription Facto |
| FPR1 Antibody | 49-275 | WB, IHC | Chm | Formyl Peptide Receptor 1 |
| FRK Antibody | 26-902 | E, WB | H, M | FRK (fyn-related kinase) |
| FTH1 Antibody | 26-903 | E, WB | H, M, R, D | FTH1 (ferritin, heavy polypeptide 1) |
| FUT4 Monoclonal Antibody | 49-241 | IHC, FACS | Chm | Fucosyltransferase 4 Fucosyltransferase |

