Immunology Antibodies
Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.
Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).
ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.
| Product Name | Catalog # | App. | Reactivity | Description |
|---|---|---|---|---|
| EAT2 Phospho Y127 Antibody | 46-835 | E, WB | H | EAT2 phospho (Y127) |
| EBI3 Antibody | 4977 | E, WB, IHC, IF | H, M, R | (IN) Epstein-Barr virus induced 3 precursor |
| EBI3 Antibody | 4967 | E, WB, IHC, IF | H, M | (CT) Epstein-Barr virus induced 3 precursor |
| EBI3 Antibody | 46-971 | E | H | (IN) EBI3 |
| ECSIT Antibody | 49-421 | E, WB, IHC | M | Evolutionarily Conserved Signaling Intermediate In |
| ECT2 Antibody | 30-812 | E, WB | H, M | ECT2 (epithelial cell transforming sequence 2 onco |
| ECT2 Antibody | 30-811 | E, WB | H, M | ECT2 (epithelial cell transforming sequence 2 onco |
| EDA Antibody | 25-972 | E, WB | H, M | EDA (ectodysplasin A) |
| EFCAB4A Antibody | 6043 | E, WB | H, M, R | (IN) EF-hand calcium binding domain 4A |
| EFCAB4B Antibody | 6045 | E, WB, IHC, IF | H, M | (CT) EF-hand calcium binding domain 4B |
| EGLN2 Antibody | 28-104 | E, WB | H | EGLN2 (egl nine homolog 2 (C. elegans)) |
| EIF2AK2 Antibody | 31-078 | E, WB | H | EIF2AK2 (eukaryotic translation initiation factor |
| EIF2S3 Antibody | 30-144 | E, WB | H, M, R, D, ZF | EIF2S3 (eukaryotic translation initiation factor 2 |
| Endoglin Antibody | 49-773 | E, IHC | H | Endoglin |
| Eotaxin Monoclonal Antibody | 38-234 | E, WB | H | Anti-Human Eotaxin, monoclonal |
| Eotaxin-3 Monoclonal Antibody | 38-238 | E, WB, N | H | Anti-Human Eotaxin-3, monoclonal |
| EPOR Antibody | 25-938 | E, WB | H, D | EPOR (erythropoietin receptor) |
| EPRS Antibody | 26-103 | E, WB | H | EPRS (glutamyl-prolyl-tRNA synthetase) |
| ERAP2 Antibody | 46-837 | E, WB | H | ERAP2 |
| ESR1 Antibody | 26-058 | E, WB | H | ESR1 (estrogen receptor 1) |
| ETS1 Antibody | 31-151 | E, WB, IHC | H, M, R, D | ETS1 (v-ets erythroblastosis virus E26 oncogene ho |

