Immunology Antibodies
Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.
Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).
ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.
| Product Name | Catalog # | App. | Reactivity | Description |
|---|---|---|---|---|
| DCLRE1C Antibody | XW-7140 | WB | H | DNA cross-link repair 1C; artemis protein |
| DDAH1 Antibody | 26-938 | E, WB | H, M, R | DDAH1 (dimethylarginine dimethylaminohydrolase 1) |
| DDAH2 Antibody | 27-196 | E, WB | H, M, R | DDAH2 (dimethylarginine dimethylaminohydrolase 2) |
| DDX54 Antibody | 28-505 | E, WB | H, D | DDX54 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 54) |
| DEPDC7 Antibody | 30-754 | E, WB | H | DEPDC7 (DEP domain containing 7) |
| DFNA5 Antibody | 30-158 | E, WB, IHC | H | DFNA5 (deafness, autosomal dominant 5) |
| DGKE Antibody | 26-054 | E, WB | H | DGKE (diacylglycerol kinase, epsilon 64kDa) |
| DGKH Antibody | 26-073 | E, WB | H, M, R | DGKH (diacylglycerol kinase, eta) |
| DIRAS1 Antibody | 26-699 | E, WB | H, M, R | DIRAS1 (DIRAS family, GTP-binding RAS-like 1) |
| DKFZP564J0863 Antibody | 26-190 | E, WB | H, M, R | DKFZP564J0863 (hypothetical protein DKFZP564J0863) |
| DLG7 Antibody | 26-109 | E, WB | H, M | DLG7 (discs, large homolog 7) |
| DNTT Antibody | 30-788 | E, WB | H, M, R | DNTT (deoxynucleotidyltransferase, terminal) |
| DPP4 Antibody | XW-7151 | ICC | H | Dipeptidylpeptidase IV (CD26) |
| DTNB Antibody | 26-124 | E, WB | H, M, R | DTNB (dystrobrevin, beta) |
| DUT Antibody | 30-136 | E, WB, IHC | H, M, R, D | DUT (dUTP pyrophosphatase) |
| DVL1 Antibody | 27-500 | E, WB | H | DVL1 (dishevelled, dsh homolog 1 (Drosophila)) |
| DXYS155E Antibody | 28-033 | E, WB, IHC | H, D | DXYS155E (splicing factor, arginine/serine-rich 17 |

