Immunology Antibodies
Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.
Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).
ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.
| Product Name | Catalog # | App. | Reactivity | Description |
|---|---|---|---|---|
| B2M Antibody | 7439 | E, WB | H | Beta-2-microglobulin |
| B3GAT1 Monoclonal Antibody | 49-192 | IHC, FACS | H, R | Beta-1,3-glucuronyltransferase 1 |
| Basigin Monoclonal Antibody | 49-195 | WB, IHC, FACS | H | Basigin |
| BATF Antibody | 25-090 | E, WB | H, M, R | BATF (basic leucine zipper transcription factor, A |
| BCAP31 Antibody | 45-019 | E, WB | H | (CT) BCAP31 / BAP31 |
| BCL2 Antibody | 31-005 | E, WB, IHC | H | BCL2 (B-cell CLL/lymphoma 2) |
| BDKRB2 Antibody | 29-643 | E, WB | H | BDKRB2 (bradykinin receptor B2) |
| Blimp-1 Antibody | 3991 | E, WB, IHC, IF | H, M, R | (NT) B-lymphocyte-induced maturation protein 1 |
| Blimp-1 Antibody | 3989 | E, WB, IF | H, M, R | (CT) B-lymphocyte-induced maturation protein 1 |
| BLK Antibody | 30-146 | E, WB | H, M, R | BLK (B lymphoid tyrosine kinase) |
| BLNK Antibody | 45-025 | E, WB | H | (CT) BLNK |
| BOP1 Antibody | 26-110 | E, WB | H | BOP1 (block of proliferation 1) |
| BRAK Antibody | 38-159 | E, WB | H | Biotin - Anti-Human BRAK |
| BRAK Antibody | 38-158 | E, WB | H | Anti-Human BRAK |
| BSA Monoclonal Antibody | 32-122 | E, WB | B | Bovine serum albumin |
| BTLA Antibody | 46-766 | E, WB | M | BTLA |

