Immunology Antibodies
Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.
Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).
ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.
| Product Name | Catalog # | App. | Reactivity | Description |
|---|---|---|---|---|
| ABCA2 Antibody | 46-787 | E | H | ABCA2 |
| ACTR2 Antibody | 30-135 | E, WB, IHC | H, M, R, D | ACTR2 (ARP2 actin-related protein 2 homolog (yeast |
| ADA Antibody | 26-611 | E, WB | H, M | ADA (adenosine deaminase) |
| ADAM33 Antibody | 30-559 | E, WB | H, M, R | ADAM33 (ADAM metallopeptidase domain 33) |
| ADAM9 Antibody | 26-131 | E, WB | H, M, R | ADAM9 (ADAM metallopeptidase domain 9 (meltrin gam |
| ADAP Antibody | 4277 | E, WB, ICC, IF | H, M | (CT) Adhesion and degranulation adapter protein |
| ADAP Antibody | 4279 | E, WB, ICC, IF | H | (NT) Adhesion and degranulation adapter protein |
| AGER Antibody | 29-611 | E, WB, IHC | H | AGER (advanced glycosylation end product-specific |
| AGER Antibody | 29-610 | E, WB, IHC | H | AGER (advanced glycosylation end product-specific |
| AGTR1 Antibody | 25-746 | E, WB | H, M, R, D | AGTR1 (angiotensin II receptor, type 1) |
| AHSG Antibody | 27-956 | E, WB | H | AHSG (alpha-2-HS-glycoprotein) |
| AID Antibody | 3091 | E, WB, ICC, IF | H, M | (CT) activation induced cytidine deaminase |
| AIM2 Antibody | 26-540 | E, WB | H | AIM2 (absent in melanoma 2) |
| AIRE Antibody | 27-660 | E, WB | H | AIRE (autoimmune regulator) |
| AIRE Antibody | 27-659 | E, WB | H | AIRE (autoimmune regulator) |
| AIRE Antibody | 27-661 | E, WB | H, M, R | AIRE (autoimmune regulator) |
| AK2 Antibody | 30-145 | E, WB | H | AK2 (adenylate kinase 2) |
| ALB Antibody | XW-7023 | E, WB | H, M, R, D, B, P | Albumin |
| Alpha-1 Acid Glycoprotein Antibody | XG-6112 | E, WB | H | Anti-α-1 Acid Glycoprotein |
| Alpha-1 Antitrypsin Antibody | XG-6111 | E, WB | H | Anti-α-1 Antitrypsin |
| ANP32A Antibody | 29-210 | E, WB, IHC | H | ANP32A (acidic (leucine-rich) nuclear phosphoprote |
| ANP32A Antibody | 29-209 | E, WB, IHC | H | ANP32A (acidic (leucine-rich) nuclear phosphoprote |
| ANP32E Antibody | 26-128 | E, WB | H | ANP32E (acidic (leucine-rich) nuclear phosphoprote |
| ANXA1 Antibody | 28-512 | E, WB, IHC | H | ANXA1 (annexin A1) |
| APBA3 Antibody | 27-226 | E, WB | H | APBA3 (amyloid beta (A4) precursor protein-binding |

