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Immunology Antibodies

Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.

Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).

ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.

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Product NameCatalog #App.ReactivityDescription
ABCA2 Antibody46-787EHABCA2
ACTR2 Antibody30-135E, WB, IHCH, M, R, DACTR2 (ARP2 actin-related protein 2 homolog (yeast
ADA Antibody26-611E, WBH, MADA (adenosine deaminase)
ADAM33 Antibody30-559E, WBH, M, RADAM33 (ADAM metallopeptidase domain 33)
ADAM9 Antibody26-131E, WBH, M, RADAM9 (ADAM metallopeptidase domain 9 (meltrin gam
ADAP Antibody4277E, WB, ICC, IFH, M(CT) Adhesion and degranulation adapter protein
ADAP Antibody4279E, WB, ICC, IFH(NT) Adhesion and degranulation adapter protein
AGER Antibody29-611E, WB, IHCHAGER (advanced glycosylation end product-specific
AGER Antibody29-610E, WB, IHCHAGER (advanced glycosylation end product-specific
AGTR1 Antibody25-746E, WBH, M, R, DAGTR1 (angiotensin II receptor, type 1)
AHSG Antibody27-956E, WBHAHSG (alpha-2-HS-glycoprotein)
AID Antibody3091E, WB, ICC, IFH, M(CT) activation induced cytidine deaminase
AIM2 Antibody26-540E, WBHAIM2 (absent in melanoma 2)
AIRE Antibody27-660E, WBHAIRE (autoimmune regulator)
AIRE Antibody27-659E, WBHAIRE (autoimmune regulator)
AIRE Antibody27-661E, WBH, M, RAIRE (autoimmune regulator)
AK2 Antibody30-145E, WBHAK2 (adenylate kinase 2)
ALB AntibodyXW-7023E, WBH, M, R, D, B, PAlbumin
Alpha-1 Acid Glycoprotein AntibodyXG-6112E, WBHAnti-α-1 Acid Glycoprotein
Alpha-1 Antitrypsin AntibodyXG-6111E, WBHAnti-α-1 Antitrypsin
ANP32A Antibody29-210E, WB, IHCHANP32A (acidic (leucine-rich) nuclear phosphoprote
ANP32A Antibody29-209E, WB, IHCHANP32A (acidic (leucine-rich) nuclear phosphoprote
ANP32E Antibody26-128E, WBHANP32E (acidic (leucine-rich) nuclear phosphoprote
ANXA1 Antibody28-512E, WB, IHCHANXA1 (annexin A1)
APBA3 Antibody27-226E, WBHAPBA3 (amyloid beta (A4) precursor protein-binding
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