Cytokines are a group of proteinaceous signaling compounds that, like hormones and neurotransmitters, are used extensively for inter-cell communication.
While hormones are secreted from specific organs to the blood and neurotransmitters are related to neural activity, the cytokines are a more diverse class of compounds in terms of origin and purpose. They are critical to the functioning of both innate and adaptive immune responses. Apart from their importance in the development and functioning of the immune system, cytokines play a major role in a variety of immunological, inflammatory and infectious diseases. They are also involved in several developmental processes during embryogenesis.
Cytokines are produced by a wide variety of cell types (both haemopoietic and non-haemopoietic) and can have effects on both nearby cells or throughout the organism, sometimes strongly dependent on the presence of other chemicals and cytokines. The cytokine family consists mainly of smaller water-soluble proteins and glycoproteins with a mass of 8-30 kDa.
ProSci has a wide variety of cytokine antibodies. These include antibodies against B cell activating factor belonging to the TNF family (BAFF), interleukin (IL), small inducible cytokine (CCL), tumor necrosis factor (TNF) and many other cytokine proteins. Additionally, ProSci offers a BAFF and Receptor Detection Set. ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each cytokine antibody.
|Product Name||Catalog #||App.||Reactivity||Description|
|PTGES Antibody||48-375||IHC||H||(NT) Prostaglandin E Synthase|
|PTGES Antibody||48-374||IHC||H||Prostaglandin E Synthase|
|PTPRC Antibody||51-084||IHC||n/a||(NT) Protein Tyrosine Phosphatase CD45|