ACTG1 Recombinant Protein | catalog# XW-RP3002
Background
Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, α, β and γ have been identified. The α actins are found in muscle tissues and are a major constituent of the contractile apparatus. The β and γ actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, γ 1, encoded by this gene, is a cytoplasmic actin found in nonmuscle cells.
FUNCTION: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
SUBUNIT: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.
Description
Specifications
Protein Accession Number
NP_001605Buffer
10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3Fusion Partner
T7 tag at N-terminusMolecular Weight
41.8 kDa (Calculated)Protein GI Number
4501887Source
E. coliTested Application
E, WB, MSStorage
Store at -70˚C. As with any protein, exposing ACTG1 recombinant protein to repeated freeze/thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.Species Reactivity
n/aPurity
>95%Reference
- Cheng,C. and Sharp,P.A.: RNA polymerase II accumulation in the promoter-proximal region of the dihydrofolate reductase and gamma-actin genes. Mol. Cell. Biol. 23 (6), 1961-1967 (2003)]